Professor Chi-Huey Wong

Professor of Chemistry at The Scripps Research Institute
President, Academia Sinica
128 Academia Road, Section 2, Nankang, Taipei, Taiwan
Tel:+886-2-2789-9400 Fax: +886-2-2785-3852
E-mail: chwong@gate.sinica.edu.tw; wong@scripps.edu

Current Research:

sugar

Group Focus

Research in the laboratory of Dr. Wong encompasses a wide variety of projects directed toward development of new chemical and enzymatic strategies and methods for the synthesis of biologically active compounds and designed molecules as mechanistic probes and inhibitors of carbohydrate-mediated biological recognitions, sequence-specific RNA recognition, and enzymatic reactions. Chemists and biochemists work on projects ranging from chemical and chemoenzymatic synthesis of bioactive compounds to enzyme engineering and development of new tools to tackle major problems in living systems. Currently, research is being performed in the following areas:

  • Chemical and enzymatic organic synthesis
  • Directed evolution and engineering of enzymes for organic synthesis
  • Development of enzyme and receptor inhibitors
  • Development of aminoglycosides and small molecules targeting RNA
  • Carbohydrate chemistry and molecular glycobiology
  • Programmable one-pot synthesis of oligosaccharides
  • Glycoprotein synthesis
  • Studies on carbohydrate-mediated recognition
  • Mechanistic study of enzymatic reactions